Best S-Equol Supplements UK 2026: Seven Products Scored on the Evidence
Seven S-equol supplements available to UK buyers, scored mainly on S-equol form and source, fillers and additives, testing and label warnings, with price as a minor factor.
Most S-equol supplements provide 10mg a day, but what their labels disclose varies widely.
None of the 7 products publishes a test report we could read. Some state how their S-equol is made and some do not; one does not say it is S-equol at all. Added ingredients range from none stated to seven, and three of the products combine S-equol with other active ingredients.
This guide explains what S-equol is, what has been studied, the safety points to check and what to look for on a label. Products are ranked only by the weighted scores in our scoring table, using the method described below.
Seven S-equol supplements at a glance, in score order
Charava S-Equol 10mg Capsules
Highest scoreOne capsule with 10mg of S-equol, described as filler-free in an HPMC capsule, with full warnings, at the lowest cost per day here. How the S-equol is made is not stated. Relative score 100 (top product = 100) · absolute score 75.5/100 · £0.90 per daily serving
Read our review
DHC Soy Isoflavone Equol (10mg S-equol)
A one-a-day Japanese tablet with 10mg of S-equol from fermented soy germ extract. It has four added ingredients, no medication warning and is shipped from Japan, so UK import charges may apply. Relative score 79.2 (top product = 100) · absolute score 59.8/100 · £0.97 per daily serving
Read our review
Garden of Life Herbals Menopause + Hair Growth
A multi-ingredient vegan softgel combining 10mg S-equol with trans-resveratrol, Keranat™ and a probiotic. The S-equol source is not stated on the page. Relative score 77.2 (top product = 100) · absolute score 58.3/100 · £1.56 per daily serving
Read our review
The Postbiotic Company Women's Wellness
A chewable tablet with 10mg S-equol from soy, fermented turmeric, fermented pomegranate and four vitamins, with full warnings but seven additives, including sweeteners. Relative score 69 (top product = 100) · absolute score 52.1/100 · £1.77 per daily serving
Read our review
Nutrined Equol Capsules
A Dutch vegetable capsule listing 12mg of "Equol" per two capsules. It does not say it is S-equol, and the retailer lists the 12mg as fermented soy extract, so the equol content is unclear. Relative score 66.8 (top product = 100) · absolute score 50.4/100 · £1.01 per daily serving
Read our review
MitoQ Hormonal Metabolic Control
A multi-ingredient capsule with 10mg S-equol from soy germ, a probiotic, chromium and vitamin D. It lists five fillers or processing aids, and its pages say it will not interfere with HRT. Relative score 65.4 (top product = 100) · absolute score 49.4/100 · £1.83 per daily serving
Read our review
Equelle Menopause Symptom Relief
The US S-equol tablet made from fermented soy germ, sold in the UK only through a reseller. It has five added ingredients and no pregnancy or age warning on the pages we read, and is the most expensive per day here. Relative score 61.2 (top product = 100) · absolute score 46.2/100 · £1.92 per daily serving
Read our review
Scores by criterion
Each product is scored 0 to 10 on every criterion. The weighted total out of 100 (the absolute score) sets the ranking. Weights were fixed before scoring and are the same for every product: 90% is on S-equol form and source, dose, fillers, testing and labelling, and 10% on price per daily serving. Anything a page does not disclose scores 0 for that item and is shown as "not disclosed": we never assume a source, an ingredient or a test we cannot see. Each product also shows a relative score (top product = 100): its absolute score divided by the top product's absolute score, multiplied by 100 (see how relative scores work). Evidence was checked on 2 November 2026. Full method.
| Rank | Product | S-equol form and source 20% |
Dose and label transparency 15% |
Fillers and additives 20% |
Testing and certificates 15% |
Label and safety warnings 15% |
Capsule or tablet, vegan and allergen clarity 5% |
Price per daily serving 10% |
Absolute score weighted total /100 |
Relative score top product = 100 |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Charava S-Equol 10mg Capsules | 6 | 10 | 10 | 0 | 9 | 10 | 10 | 75.5 | 100 |
| 2 | DHC Soy Isoflavone Equol (10mg S-equol) | 9 | 10 | 2 | 0 | 8 | 3 | 9.3 | 59.8 | 79.2 |
| 3 | Garden of Life Herbals Menopause + Hair Growth | 6 | 10 | 5 | 0 | 7 | 10 | 5.8 | 58.3 | 77.2 |
| 4 | The Postbiotic Company Women's Wellness | 9 | 8 | 0 | 0 | 9 | 7 | 5.1 | 52.1 | 69 |
| 5 | Nutrined Equol Capsules | 6 | 4 | 4 | 0 | 7 | 10 | 8.9 | 50.4 | 66.8 |
| 6 | MitoQ Hormonal Metabolic Control | 9 | 9 | 1 | 0 | 4 | 10 | 4.9 | 49.4 | 65.4 |
| 7 | Equelle Menopause Symptom Relief | 9 | 8 | 1 | 0 | 4 | 7 | 4.7 | 46.2 | 61.2 |
Swipe horizontally to see all criteria.
The top product is 15.7 points ahead of the second. None of the 7 products publishes a readable test report, so all score 0 for testing. Three products are multi-ingredient (marked in their reviews); their price per day also pays for the other ingredients, so daily costs are not like for like.
S-equol: what it is and what has been studied
Equol is made from daidzein, an isoflavone in soy, by certain gut bacteria. The form the body makes is S-equol. Studies suggest that only a minority of people in Western countries make equol from the soy they eat, compared with a larger share in East Asian populations. S-equol supplements supply it directly; the ingredient in most of them is made by fermenting soy germ.
No nutrition or health claim is authorised for equol or soy isoflavones in Great Britain. The research below is described so you know what has been studied. It is not a claim that any product in this guide has any effect, and none of these studies tested the products here.
No authorised claims
The GB nutrition and health claims register has no authorised health claim for equol or soy isoflavones. Statements on product pages about menopause, hot flushes, skin, bone, hair, weight or blood sugar are not authorised claims.
How equol is formed
Reviews describe how gut bacteria convert daidzein to S-equol, why people differ in whether they produce it, and how it behaves in the body.
Studies in menopausal women
Small randomised trials, mostly in Japan and the US and mostly using one manufacturer's fermented soy germ ingredient, have looked at menopausal symptom questionnaires and markers of bone turnover. A 2019 meta-analysis pooled a small number of these trials. The trials were small, short and differed in design.
Aso et al., 2012 · Jenks et al., 2012 · Tousen et al., 2011 · Daily et al., 2019
Regulatory status
We found no S-equol entry in the GB novel-food register or the EU Union list of novel foods. The European Commission lists an ongoing novel-food application for an S-equol-rich fermented soy germ ingredient, proposed for adults and excluding pregnant and breastfeeding women. Ask the brand if you want to know how its S-equol is authorised.
These points describe published research on equol generally. They are not health claims and not claims about any product in this guide.
Safety points to check before you buy
Pregnancy, breastfeeding and under-18s
Do not take S-equol if you are pregnant, trying to conceive or breastfeeding, and do not give it to children or under-18s. One of the 7 product pages we read has no pregnancy warning.
Hormone-sensitive conditions
Equol interacts with oestrogen receptors. If you have or have had a hormone-sensitive condition, such as breast or endometrial cancer, endometriosis or fibroids, speak to your doctor before taking it. The European Food Safety Authority has assessed isolated isoflavone supplements in peri- and post-menopausal women and noted that women with or with a history of oestrogen-dependent cancer were outside its assessment.
Medicines, including HRT
If you take HRT, hormonal contraception, thyroid medicine, tamoxifen or other medication, speak to your doctor or pharmacist first. Treat any statement that a supplement will not interfere with HRT with caution.
Soy allergy
Most S-equol ingredients are made from soy. If you are allergic to soy, check the label, and ask the brand where its S-equol comes from if the label does not say.
Keep to the directed dose. Do not combine several products that contain S-equol or soy isoflavones without advice. Stop and seek medical advice if you have side effects.
What to look for in an S-equol supplement
01. "S-equol", with the amount
Look for S-equol named, with the amount per daily serving. A product that says only "equol", or gives the weight of a soy extract, may contain less.
02. How it is made
Look for the source, for example fermented soy germ. It also tells you whether soy is present.
03. A certificate you can read
"Third-party tested" means little without a report showing the batch, the S-equol content and heavy metals, from an accredited lab. None of the products here publishes one.
04. Single or combined
Some products add other actives, such as resveratrol, probiotics or vitamins. Check you are not doubling up with something you already take.
05. Few fillers and additives
Check the full ingredient list. Starches, cellulose, silicon dioxide, stearates and sweeteners are common.
06. Clear warnings
A responsible label covers pregnancy and breastfeeding, under-18s, hormone-sensitive conditions, HRT and other medicines, and a daily maximum.
Label claims to treat with caution
Menopause and hot-flush claims
No health claim is authorised for equol in Great Britain, so statements that a product relieves hot flushes or supports menopause are not authorised claims.
Skin, bone, hair and metabolism claims
The same applies to claims about skin, bone, hair growth, weight or blood sugar made for S-equol.
"Safe with HRT" or "no side effects"
Statements that play down interactions or risks are not a substitute for advice from your doctor.
Reviews and endorsements
Be wary of testimonials you cannot verify, or expert quotes without a full name and qualification.
Seven S-equol supplements, in score order
Products appear in order of their absolute score from the scoring table. We read each product page, and any testing documents and label images linked from it, on 2 November 2026. Where a brand states something we could not verify, we say it is stated by the brand. We have not bought or tested these products ourselves.
Charava S-Equol 10mg Capsules
One capsule with 10mg of S-equol, described as filler-free in an HPMC capsule, with full warnings, at the lowest cost per day here. How the S-equol is made is not stated.
Reasons to choose it
- Lowest cost per daily serving here (£0.90 on the 90-day option).
- No fillers or flow agents stated: S-equol in an HPMC capsule (stated by Charava).
- The most complete warnings here, including hormone-sensitive conditions, HRT and hormonal contraception.
Points to consider
- Does not say how its S-equol is made or where it comes from.
- No formal ingredient list, and the page makes menopause, skin and bone statements that are not authorised claims in Great Britain (stated by Charava).
Our verdict: A simple single-ingredient capsule with strong warnings at the lowest price here. Publishing the S-equol source and a test report would make it much easier to verify.
DHC Soy Isoflavone Equol (10mg S-equol)
Strengths
- States the source: fermented soy germ extract.
- Clear dose: 10mg S-equol in one tablet a day.
- Second-lowest cost per day before shipping and import charges.
Considerations
- Four added ingredients, including two flow agents.
- No medication warning.
- Sold in US dollars from Japan by a retailer; UK import charges are the buyer's responsibility (stated by the retailer).
Our verdict: Clear about its source and dose, but more additives, thinner warnings and import costs to factor in.
Garden of Life Herbals Menopause + Hair Growth
Strengths
- Clear dose and pack information.
- Vegan softgel, certified vegan and gluten-free, with a soy allergen statement.
- Pregnancy, medication and children warnings.
Considerations
- Not a single-ingredient S-equol product: also contains resveratrol, Keranatâ„¢ and a probiotic.
- S-equol source not stated.
- Makes hot-flush and hair-growth claims that are not authorised in Great Britain (stated by Garden of Life).
Our verdict: Clearly labelled, but a combination product with no published testing.
The Postbiotic Company Women's Wellness
Strengths
- States the S-equol amount and that it comes from soy.
- Full warnings, including hormone-sensitive conditions.
- Every active ingredient listed with its amount.
Considerations
- Not a single-ingredient product: S-equol is one of seven actives.
- Seven additives, including three sweeteners: the lowest fillers score here.
Our verdict: Transparent labelling and warnings, but a sweetened multi-ingredient chew rather than an S-equol supplement.
Nutrined Equol Capsules
Strengths
- Low cost per daily serving (£1.01).
- Vegetable capsule with a soy allergen statement.
- Pregnancy and medication warnings.
Considerations
- Does not say S-equol, and the 12mg could be the soy extract rather than equol.
- Three fillers or flow agents.
- The retailer page makes hormonal and brain-health statements that are not authorised claims in Great Britain (stated by the retailer).
Our verdict: Inexpensive, but you cannot tell from the pages how much S-equol it contains.
MitoQ Hormonal Metabolic Control
Strengths
- States the S-equol amount and source.
- Vegetarian capsule, gluten-free.
- Pregnancy and medication warnings.
Considerations
- Not a single-ingredient product.
- Five fillers or processing aids.
- Statements that it will not interfere with HRT and has no known major side effects play down risks; weight and blood-sugar claims are not authorised in Great Britain (stated by MitoQ).
Our verdict: Clear on dose and source, but many additives and reassurances about safety that we would want backed up.
Equelle Menopause Symptom Relief
Strengths
- States the source: fermented soy germ.
- Clear daily S-equol amount.
- Soy allergen statement.
Considerations
- Only available in the UK through a reseller; the brand ships to the US only.
- Five added ingredients.
- No pregnancy, age or do-not-exceed warning found; highest cost per day here.
Our verdict: A well-known S-equol tablet, but hard to buy in the UK and thinly labelled for UK buyers.
Comparisons refer to the named product and pack, not the brand's whole range. Specifications, prices and stock can change; we last checked them on 2 November 2026. "Not disclosed" means we could not find it on the pages we read, not that a product is untested or poor quality.
S-equol supplements side by side
| Rank | Product | Absolute score /100 | Relative score (top product = 100) | Pack and price | Price per daily serving | S-equol per serving | S-equol form and source | Other ingredients | Certificate of analysis | Warnings on the page | Where we read it |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Charava S-Equol 10mg Capsules | 75.5 | 100 | 30 capsules, £29.99; 90-day option £80.99 (£27.00 per 30 capsules) | £0.90 (1 capsule) | 10mg S-equol per capsule; 1 capsule a day; 30 servings | S-equol named; how it is made (for example fermented soy germ) not stated | None stated: "filler-free formula and an HPMC vegan capsule" (stated by Charava); no formal ingredient list on the page | "Third-party tested" statements only; no report published, and the testing widget on the page shows no S-equol results | Not if pregnant, trying to conceive or breastfeeding; speak to a doctor if you have or had a hormone-sensitive condition, take HRT, hormonal contraception or other medication; not for under-18s; do not exceed | Brand site (UK) |
| 2 | DHC Soy Isoflavone Equol (10mg S-equol) | 59.8 | 79.2 | 30 tablets, US$38.99 (about £29.05; no 3-pack sold) | £0.97 (1 tablet), excluding shipping and import charges | 10mg S-equol per tablet; 1 tablet a day; 30 tablets | S-equol from fermented soy germ extract (stated) | Starch, silicon dioxide, calcium stearate, methyl cellulose | None published | Do not exceed; not for pregnant or breastfeeding women; not for children; consult a professional if you have gynaecological conditions; no medication warning found | Japanese retailer, ships to the UK |
| 3 | Garden of Life Herbals Menopause + Hair Growth | 58.3 | 77.2 | 30 softgels, £46.75 (no 3-pack sold) | £1.56 (1 softgel) | 10mg S-equol per softgel, plus trans-resveratrol 150mg and Keranat™ 300mg; 30 softgels | S-equol named; source not stated on the page | Olive oil, sunflower lecithin, candelilla wax, fruit and vegetable concentrates (flavour and colour); vegan softgel | None published | Consult a practitioner if pregnant, planning pregnancy, nursing, taking medication or anticipating surgery; not for children; no do-not-exceed statement | iHerb UK |
| 4 | The Postbiotic Company Women's Wellness | 52.1 | 69 | 60 tablets (30 days), £52.99 one-off; the 90-day option is subscription only | £1.77 (2 tablets) | 10mg S-equol per 2-tablet serving (amount per tablet not stated); 60 tablets | S-equol "from soy isoflavones" (stated) | Isomalt, dextrose, agave sweetener, natural flavouring, citric acid, silicon dioxide, magnesium stearate | Lists tests on its fermented turmeric (heavy metals, glyphosate, microbes); no certificate document published | Not in pregnancy or breastfeeding; doctor first if hormone-sensitive condition or medication; do not exceed; contains soy | Brand site (UK) |
| 5 | Nutrined Equol Capsules | 50.4 | 66.8 | 120 capsules, £60.72 (no 3-pack sold) | £1.01 (2 capsules) | 12mg per 2 capsules: "Equol" on the brand label, "fermented extract of soy" on the retailer page; per-capsule amount not stated | Fermented soy (stated); S-form not stated | Microcrystalline cellulose, rice starch, silicon dioxide; HPMC capsule | None published | Do not exceed; consult a doctor if pregnant, breastfeeding or under medical treatment; keep out of reach of children | Naturitas UK |
| 6 | MitoQ Hormonal Metabolic Control | 49.4 | 65.4 | 1 month £60.95; 3 months £164.57 one-off (£54.86 per month) | £1.83 (1 capsule) | 10mg S-equol per capsule, plus B. breve, chromium 200mcg and vitamin D3 7.5mcg; 1 capsule a day | S-equol "from soy germ" (stated) | Tapioca starch, microcrystalline cellulose, silica, dicalcium phosphate, water; hypromellose capsule | "Tested for purity" statement only; no report published | Do not take while pregnant or lactating; speak to a doctor if on hormonal birth control or diabetes medication; states it "won't interfere with HRT" and has "no known major side effects" | Brand site (UK store) |
| 7 | Equelle Menopause Symptom Relief | 46.2 | 61.2 | 60 tablets, £57.45 (no 3-pack sold) | £1.92 (2 tablets) | 10mg S-equol per 2-tablet serving (amount per tablet not stated); 60 tablets | S-equol from fermented soy germ (stated by the brand) | Dicalcium phosphate, silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose; coating (hypromellose, glycerin, hydroxypropyl cellulose) | None published | Advice on timing with thyroid and iron medicines and to discuss with a doctor; no pregnancy, age or do-not-exceed statement found | UK reseller (brand ships to the US only) |
Swipe horizontally to compare all columns. Price is based on each brand's 3-pack price divided by 3 to give a single-pack price, then per daily serving; where no 3-pack is sold we use the single-pack price. Prices are one-off prices (no subscriptions), excluding delivery, checked 2 November 2026. One serving is the directed daily amount. The DHC price is converted from US dollars at the European Central Bank reference rates of 2 November 2026 (US$1 = £0.74518) and excludes shipping, import VAT and any duty.
S-equol: your questions answered
S-equol, safety and this guide
What is S-equol?
Equol is a compound that some people's gut bacteria make from daidzein, an isoflavone found in soy. S-equol is the form the body makes. Studies suggest that only a minority of people in Western countries produce equol from the soy they eat. Supplements supply S-equol directly, usually made by fermenting soy germ.
Does S-equol have any approved health claims?
No. There is no authorised nutrition or health claim for equol or soy isoflavones in Great Britain, so statements on product pages about menopause, hot flushes, skin, bone, hair or metabolism are not authorised claims. We make no claims about what any product does.
Who should not take S-equol?
Do not take S-equol if you are pregnant, trying to conceive or breastfeeding, and it is not for children or under-18s. If you have or have had a hormone-sensitive condition (such as breast or endometrial cancer, or endometriosis), or take HRT, hormonal contraception, thyroid medicine or any other medication, speak to your doctor or pharmacist first.
Is S-equol the same as soy isoflavones?
No. Soy isoflavone supplements supply daidzein and genistein, which some people convert to equol in the gut. S-equol supplements supply equol itself. Some products in this guide combine S-equol with other ingredients, so check the full label.
What is the regulatory status of S-equol in Great Britain?
We found no entry for S-equol in the GB novel-food register or the EU Union list of novel foods when we checked. The European Commission lists an ongoing novel-food application for an S-equol-rich fermented soy germ ingredient. If you want to know how a product's S-equol is authorised, ask the brand.
How did you choose and score the products?
We looked for S-equol supplements that UK buyers can order and verified 7 products on live product pages on 2 November 2026. Only four single-ingredient S-equol products were available to UK buyers, so we also included three multi-ingredient products and label them clearly. We scored each on seven fixed criteria weighted 90% on quality and labelling and 10% on price per daily serving. Anything a page did not disclose scored 0. We did not buy or test the products ourselves.
Do you earn money from this guide?
We may earn a commission when you buy through links on this page. This doesn't affect how we rank products: every product is assessed with the same method. We scored every product with the same fixed criteria and weights, and we show every score.
Check the warnings and what the label says about S-equol
S-equol has no authorised health claims in Great Britain. If you are pregnant, trying to conceive or breastfeeding, under 18, take HRT, hormonal contraception or any other medication, or have or have had a hormone-sensitive condition, speak to your doctor before taking it.
Charava S-Equol 10mg Capsules has the highest score (75.5/100): it states no fillers, has the most complete warnings and the lowest cost per day, but it does not say how its S-equol is made and publishes no test report. DHC Soy Isoflavone Equol (10mg S-equol) is 15.7 points behind; it states a fermented soy germ source but has more additives and is imported from Japan. No product here publishes a readable test report.
How we score products
We compared 7 S-equol supplements available to UK buyers, using each product page, its label images and any testing documents linked from it, read on 2 November 2026. Each product was scored 0 to 10 on seven criteria. The weights and point rules were fixed before scoring and are identical for every product. If a page does not disclose something, that item scores 0 and we say "not disclosed". Figures a brand states are credited the same way for every brand, and described as stated by the brand where we could not verify them.
- S-equol form and source (20%). S-equol (the S-form) named (3 points); how it is made or its source stated, such as fermented soy germ (3); S-equol per daily serving stated (3); S-equol content shown on a readable certificate (1).
- Dose and label transparency (15%). S-equol per daily serving stated (3); per capsule or tablet stated (2); no conflicting dose figures (3); units and servings per pack stated (2, or 1 if only one is given).
- Fillers and additives (20%). Starts at 10. We deduct 2 points for each bulking agent or filler, flow agent, sweetener, preservative or colour, and 1 point for each emulsifier, flavouring, antioxidant, acidity regulator, or processing aid, oil, wax or disintegrant. The capsule or softgel shell, a tablet coating, the S-equol ingredient and declared active ingredients are not deducted. Where a brand states there are no fillers and lists no other ingredient, we take that as stated. Minimum 0.
- Testing and certificates (15%). A readable test report for this product published (4); heavy-metal results on it (2); the lab's accreditation shown (2); results matched to batches on sale (2). Statements such as "third-party tested" score 0.
- Label and safety warnings (15%). Complete ingredient list (2, or 1 if partial); a pregnancy or breastfeeding warning (2); a medication caution (2); a caution for hormone-sensitive or gynaecological conditions (2); an age statement (1); a do-not-exceed statement (1). A statement playing down risks or interactions loses 2 points.
- Capsule or tablet, vegan and allergen clarity (5%). Capsule or softgel material, tablet coating, or chewable form named (4); vegan or vegetarian status stated (3); an allergen or gluten statement (3).
- Price per daily serving (10%). 10 × (lowest price per daily serving ÷ this product's price per daily serving). Price is based on each brand's 3-pack price divided by 3 to give a single-pack price, then per daily serving; where no 3-pack is sold we use the single-pack price. We use one-off prices, not subscriptions, excluding delivery, from the page a UK buyer would order from.
Relative scores (top product = 100). A product's relative score is its absolute score (weighted total out of 100) divided by the absolute score of the top product in this guide, multiplied by 100 and rounded to one decimal place. It shows how each product compares with the best one we assessed. It is not a percentage of our criteria met: the top product, Charava S-Equol 10mg Capsules, scored 75.5/100 on our absolute criteria. The same calculation is applied to every product, so it does not change the order.
Only four single-ingredient S-equol products were available to UK buyers when we checked (Charava, DHC, Nutrined and Equelle), so we also included three multi-ingredient products that contain 10mg of S-equol a day and label them as such. We found no S-equol listings on Amazon UK, and we left out a marketplace listing priced far above the brand's own. Equelle's brand site ships to the US only, so we used a UK reseller. The ranking is an editorial judgement based on these scores. It is not a clinical comparison, an independent certification or a laboratory test, and we did not buy or test any product. Commission is explained in the note at the top of this page.
Guidance, regulation and references
1. GB nutrition and health claims register
Department of Health and Social Care. No authorised health claim exists for equol or soy isoflavones.
View on gov.uk2. Setchell KD, Clerici C. Equol: history, chemistry, and formation.
J Nutr. 2010;140(7):1355S-1362S. PMID 20519412.
View on PubMed3. Aso T, Uchiyama S, Matsumura Y, et al. A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.
J Womens Health (Larchmt). 2012;21(1):92-100. PMID 21992596.
View on PubMed4. Jenks BH, Iwashita S, Nakagawa Y, et al. A pilot study on the effects of S-equol compared to soy isoflavones on menopausal hot flash frequency.
J Womens Health (Larchmt). 2012;21(6):674-682. PMID 22409590.
View on PubMed5. Tousen Y, Ezaki J, Fujii Y, et al. Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial.
Menopause. 2011;18(5):563-574. PMID 21252728.
View on PubMed6. Daily JW, Ko BS, Ryuk J, et al. Equol decreases hot flashes in postmenopausal women: a systematic review and meta-analysis of randomized clinical trials.
J Med Food. 2019;22(2):127-139. PMID 30592686.
View on PubMed7. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS). Risk assessment for peri- and post-menopausal women taking food supplements containing isolated isoflavones.
EFSA Journal. 2015;13(10):4246.
View on EFSA8. European Commission. Summary of novel food application: fermented soy germ containing S-equol (SE5-OH), applicants Nutrition & Santé SAS and Otsuka Pharmaceutical Co. Ltd.
Ongoing application listed by the European Commission.
View on europa.eu9. Product pages
Brand product pages, label images and linked certificates, read 2 November 2026.
Charava · DHC (via WowNippon) · Garden of Life (via iHerb) · The Postbiotic Company · Nutrined (via Naturitas) · MitoQ · Equelle (via British Vita)